about endometriosis
Endometriosis is a chronic, complex, yet relatively common gynecological disorder, reportedly affecting 1 in 10¹ adult and adolescent women. Endometriosis causes tissue similar to the lining of the uterus to grow outside the uterus, which can cause severe pelvic pain and make it harder to become pregnant.
Endometriosis has a significant impact on society, public health, and the economy. It can cause severe pain, fatigue, depression, and anxiety which can negatively affect quality of life for those impacted. In some cases, endometriosis can even lead to infertility.
endometriosis symptoms & causes
Although a small percentage of women with endometriosis have no symptoms, most patients with endometriosis often experience severe pelvic pain, especially during menstrual periods.
Some women also experience:
— Chronic pelvic pain
— Heavy bleeding during periods or between periods
— Difficulty becoming pregnant
— Bloating or nausea
— Fatigue
— Depression or anxiety
Symptoms often improve after menopause, but not always.
Endometriosis symptoms can vary from woman to woman, and presentation is not uniform. As a result, healthcare providers are not always able to easily or effectively diagnose the condition. Individuals may be symptomatic for years before receiving an accurate diagnosis.
Retrograde menstruation is the most broadly adopted theory for disease cause. However, there is no definitive evidence, and many other competing theories also exist.
unmet needs presented by endometriosis
Disease stigma
Societal normalization of women’s pain and stigma concerning menstrual issues result in delayed disease diagnosis and management.
Late/Mis-diagnosis
The current diagnostic gold standard often requires invasive surgical procedures, leading clinicians to rely on empiric treatment and patients to experience delayed diagnosis for an average of 6-12 years
Treatment issues
SILOED APPROACH
Endometriosis is a chronic systemic disease, but current products are treating it as a pelvic-only issue.
LACK OF TRUE INNOVATION
All available treatments still focus on the hormone pathway or pain management and are often ineffective in halting the course of the disease, leaving many patients with inadequate symptom management.
LIMITED FERTILITY IMPROVEMENT
Surgery has not been correlated with improvements in fertility, and patients cannot get pregnant when using hormonal treatment.
SAFETY CONCERNS
Limited options are available for long-term treatment without side effects, and treatment often requires invasive measures like laparoscopy or hysterectomy surgery that come with risks.
Read more about endometriosis
symptoms and causes
Learn about the unmet needs
that endometriosis presents
endometriosis symptoms & causes
Although a small percentage of women with endometriosis have no symptoms, most patients with endometriosis often experience severe pelvic pain, especially during menstrual periods.
Some women also experience:
— Chronic pelvic pain
— Heavy bleeding during periods or between periods
— Difficulty becoming pregnant
— Bloating or nausea
— Fatigue
— Depression or anxiety
Symptoms often improve after menopause, but not always.
Endometriosis symptoms can vary from woman to woman, and presentation is not uniform. As a result, healthcare providers are not always able to easily or effectively diagnose the condition. Individuals may be symptomatic for years before receiving an accurate diagnosis.
Retrograde menstruation is the most broadly adopted theory for disease cause. However, there is no definitive evidence, and many other competing theories also exist.
unmet needs presented by endometriosis
Disease stigma
Societal normalization of women’s pain and stigma concerning menstrual issues result in delayed disease diagnosis and management.
Late/Mis-diagnosis
The current diagnostic gold standard often requires invasive surgical procedures, leading clinicians to rely on empiric treatment and patients to experience delayed diagnosis for an average of 6-12 years.4
Treatment issues
SILOED APPROACH
Endometriosis is a chronic systemic disease, but current products are treating it as a pelvic-only issue.
LACK OF TRUE INNOVATION
All available treatments still focus on the hormone pathway or pain management and are often ineffective in halting the course of the disease, leaving many patients with inadequate symptom management.
LIMITED FERTILITY IMPROVEMENT
Surgery has not been correlated with improvements in fertility, and patients cannot get pregnant when using hormonal treatment.
SAFETY CONCERNS
Limited options are available for long-term treatment without side effects, and treatment often requires invasive measures like laparoscopy or hysterectomy surgery that come with risks.
how is Heranova
addressing endometriosis?
Heranova™ is actively pursuing the development and distribution of groundbreaking diagnostics and treatments specifically for endometriosis, including a first-of-its-kind blood test that provides a ”detected/not detected“ endometriosis diagnosis — HerResolve™.
indication
PRODUCT
DESCRIPTION
pre-clinical
clinical
launched
Endometriosis
HerResolveTM
First-in-class blood-based diagnostic test. Endometriosis is a highly debilitating disease impacting 10% of reproductive-age women, but the current gold standard for confirming diagnosis is laparoscopic surgery, which can often result in mis- or late diagnosis.4
Diagnostic test for endometriosis
Endometriosis
HerResolveTM
Diagnostic test for endometriosis
Launched
First-in-class blood-based diagnostic test. Endometriosis is a highly debilitating disease impacting 10% of reproductive-age women, but the current gold standard for confirming diagnosis is laparoscopic surgery, which can often result in mis- or late diagnosis.4
providing women
a new diagnostic option
The current gold standard for confirming endometriosis diagnosis is laparoscopic surgery, which can often result in mis- or late diagnosis.4 HerResolve provides a diagnostic assessment for endometriosis with a simple blood test.
